MND Analytic File, 1991 LANL Report.
- Dataset i.d.
- mdsmra01
- Summary
- MND Analytic File, 1991 LANL Report.
- Alternate Name
-
- Sites
- Mound Plant.
- Description
- This analytic data set consists of one file generated
for a cohort mortality study, published as a LANL
Report, of white males employed at the Mound Plant.
A cohort mortality study of workers was conducted to
test for an association between mortality and
employment at the Mound Plant. The study examined
differences in mortality for workers at the plant
during its polonium-210 era (1943-1959) and for its
plutonium-238 era (1960-1980) by computing period-
specific standardized mortality ratios (SMRs) based on
U.S. rates. The analysis focused on 4,697 white and
presumed white males who were employed between April 1,
1942, and December 31, 1979, at the Mound Plant. SMRs
of 96 were observed for both all causes and for all
cancers for the study period (1943-1979). No SMR was
significantly greater than 100 for these workers. A
significantly elevated SMR for lung cancer (SMR = 204,
90% CI = 140, 290) was observed for workers employed
during World War II (1943- 1945). Similar results were
noted for all causes of death, all cancers, cancers of
the rectum, nonmalignant respiratory diseases, and all
injuries during this time period. SMRs for these
causes of death during the polonium era, but after
World War II, were not elevated. No elevated SMRs were
observed during the plutonium era. A very strong
healthy worker effect was observed for workers in the
plutonium era, although the length of follow-up for
these workers was relatively short.
The single analytic file (ANFILE) in this data set
contains demographic and vital status data for 4,697
white males and presumed white males who were employed
between April 1, 1942, and December 31, 1979. Not
included in the analytic file are workers employed less
than 30 days during this period, workers with unknown
birth dates, and workers with both unknown hire and
termination dates. No exposure data are included in
the file.
Vital status was determined for 97.6% (4,588) of the
workers in this file. Death certificates were obtained
for 97% (803) of the known deaths.
The Mound Plant has been a center for the separation,
chemistry, and metallurgy of polonium-210 and
processing of plutonium-238 for heat sources. Other
small research projects involved radium and thorium.
Workers could have been exposed to external and
internal sources of radiation; however, this analysis
did not examine exposure data.
- Citations
- REYES91 , M. Reyes, G. S. Wilkinson, G. L. Tietjen, L.
D. Wiggs, W. A. Galke, "Mortality Among Workers at the
Mound Facility, a Preliminary Report," Los Alamos
National Laboratory report LA-11997-MS (April 1991).
- Notes
- VER_DATE Data provided to CEDR (Comprehensive
Epidemiologic Data Resource) 07/21/92 (analytic file
was frozen at time of original analysis).
END_STDY Vital status follow-up through 12/31/79 is
about 98%.
ENDPOINT Mortality.
EXPOSURE (exposure agent|type|measurement method):
Exposure assessed by calendar period of work and
duration of work.
- Earliest exposure
-
- Latest exposure
-
- Latest Followup
-
- Cohort Size
- 4697
- Races
- White $ presumed white
- Sexes
- male $ presu
- Diseases
- All causes of death.
- Exposure Types
-
- Exposure Agents
-
- Methods
-
- Contacts
- Wiggs , Laurie , 505 667-8234 , 505 665-5643.$
Galke , Warren , 505 667-6488 , 505 665-5643.