Radiation epidemiology

This page started out life as a collection of materials about the epidemiology of (suspected) radiation-induced disease. It now contains pointers to other information perhaps only indirectly related to its original purpose. Browse anyway; it'll be good for you.

*** Update 2023 ***

This page was created in the 1990s and is no longer maintained. If you have comments or questions I might (might!) answer mail at kymatsdfdotorg.
Karl Morgan -- The Father of Health Physics
Karl Morgan was the founder of Health Physics, a discipline which approaches questions of radiation dose and effects primarily from a physical rather than a biological perspective. He was instrumental in showing that there is no safe dose of radiation. He resigned his position as Head of Health Physics at Oak Ridge in 1972 when he was ordered by his superiors to suppress information in his possession about the toxicity of plutonium. He subsequently worked as a private consultant on behalf of radiation victims, including Karen Silkwood. He believes that the offically-defined "permissible levels" of radiation are much higher than they should be.

Recent Studies of Low-Level Radiation and Implications for Medicine and the Nuclear Industry Sep 26 & 27, 1998
Symposium announcement.

A note on "statistical significance"

Some basic problems of epidemiology

Measuring statistically significant excess death rate change
This note is taken from Deadly Deceit, Low-Level Radiation, High-Level Coverup, by Dr. Jay Gould & Benjamin A. Goldman, with Kate Millpointer, 1991. Apart from touching on the problems of determining "excess deaths", it also indicates the historical lack of publicity "contrary" results have obtained. Jay Gould's Afterword includes at least one interesting historical footnote to Italy's decision to pull out of nuclear power.

Radiation measurement and units

Radiation and risk

Biological effects of Radiation
[From the TRIUMF Safety Group: Radiation Protection Training Course].

RISK ASSESSMENT: CLAIMING TO ESTABLISH 'SAFETY'
ENVIRONMENT & HEALTH BACKGROUND REPORT. Risk assessment is an evolving process based mainly upon toxicology, but it is also based upon a broad background of knowledge in other fields: chemistry, physiology, molecular biology, environmental transport processes [how chemicals move through the environment], and applied statistics.
[from Envirolink]

Radiation damage and atomic blast

Radiation has widespread effects on cell
Although it is widely held that radiation only has cancer-causing effects when it strikes the nucleus, or ``command center'' of a cell, a new study suggests that radiation can also trigger cancer through its effects on the cell cytoplasm, the fluid medium that fills the cell.

Ionizing Radiation and Cancer by John D Boice
[From the US NCI]

Radiation May Cause DNA Changes
Cells may be more sensitive to genetic damage caused by radiation from radon gas than previously believed, according to research that found high energy particles do not need to hit the nucleus of a cell to cause DNA changes.

Models of Cellular Radiation Action
A brief reference to a good survey and summary of then-recent results (1987).

Radiation damage in molecules and living cells

Ionising radiation epidemiology

Low level radiation epidemiology

Non-ionising radiation research

Sources of information on biological effects [of radiation]
The principal harmful radiation effects, the condition for their occurrence and the source of information about them.
NB that "Any exposure" is tentatively listed under "Circumstances" associated with "Late radiation effects".
[From the Chernobyl Project at IAEA]

The American Nuclear Society's Worldwide Electronic Resource (ANSWER)
A fresh resource of nuclear science and technology which are very important: nuclear medicine, nuclear energy, food irradiation, and nuclear techniques used in manufacturing and processing industries.
[See also the ANSWER's Nuclear Web list].

Radiation Safety
The usefulness of radiation [about 17 percent of the world's electricity is supplied by nuclear power plants] means that many people receive small doses of radiation from artificial sources as well as doses from nature. The IAEA has produced this booklet in order to enhance public understanding about the sources and effects of radiation, and to describe the measures that have been developed internationally to ensure the safe use of radiation.

Comprehensive Epidemiologic Data Resource Reference Desk
(Note some basic abstracts under "Special Materials from Government Agencies and Universities")
[See also Comprehensive Epidemiologic Data Resource to browse and/or upload classic datasets, etc.]

Los Alamos National Laboratory Publications On-line
The Los Alamos Library has taken a major initiative, called the Library Without Walls project, to scan all Los Alamos technical reports into digital documents in Adobe Acrobat PDF format. One major on-line resource is the Los Alamos Library Catalog. There is a web page describing the Technical Report Resources available and a page for non-LANL customers on How to Obtain an Unclassified Technical Reports, either in digital or paper format. There is also a page listing other recent Los Alamos publications in addition to its technical reports.
[As at 30 Jan 1997 the search catalogue function is done via Telnet (shudder)].

Radiation Protection and the Human Radiation Experiments
Largish PDF files for download
[Los Alamos Science Number 23, 1995]. Radiation, Cancer, and Risk - Three Primer; Radiation, Cell Cycle, and Cancer; Radiation and Risk a hard look at the data; A Brief History of Radiation Protection Standards; Follow-up Studies, Expert Opinions, and Future Prospects (opinions about the Plutonium Injection Experiments); Introduction to the Human Studies Project (the Human Plutonium Injection Experiments); A True Measure of Exposure.

Caltech Radiation Safety Manual
The objective of this manual is to provide the user of ionizing radiation sources with a ready reference to regulatory agency requirements, Caltech organization lines, and responsibilities and operating procedures relevant to the use of radioactive materials and radiation producing machines. Several appendices are included to assist in radiation exposure and shielding calculations, and to describe radioisotope workplace and decontamination standards. Additional training materials are available to describe safety precautions to be used when handling specific radioisotopes, and for radiation producing machines such as x-ray diffraction machines and particle accelerators.

Guide For Safe Handling Of Radioactive Sources. A Primer On The Effects Of Exposure To Ionizing Radiation
Exposure to "natural" radiation from cosmic rays, as well as radioactive materials in the soil and building materials, is unavoidable. The additional hazards from "artificial" radiation sources, such as X-ray machines, radionuclides, the burning of fossil fuels, nuclear power plants, airline travel, etc., are amenable to some degree of control. While it is not yet possible to say exactly how bad exposure to ionizing radiation can be to an organism, it is prudent to minimize all exposure to all ionizing radiation. The material presented here is intended to assist you in safely using radioactive sources in this laboratory. References, listed on page 6, should be consulted for a more extensive treatment.

National Air and Radiation Environmental Laboratory
The National Air and Radiation Environmental Laboratory (NAREL) is a comprehensive environmental laboratory managed by the U.S. Environmental Protection Agency's Office of Radiation and Indoor Air (ORIA). NAREL provides services to a wide range of clients, including other EPA offices, Federal and State agencies, and, in some cases, the private sector. NAREL facilities incorporate state-of-the-art laboratory technology and equipment and include the latest health and safety techniques, as well as strict monitoring and control of laboratory emissions.

Environmental Health (WHO)
The term "health and environment" encompasses the health consequences of interactions between human populations and the whole range of factors in their physical - natural and man-made - and social environment. The interdependence of health, development and environment is manifold and complex, but two aspects predominate: how well the environment can sustain life and health, and how free the environment is of hazards to health.

Radiation and Life
Background radiation is that which is naturally and inevitably present in our environment. Levels of this can vary greatly. People living in granite areas or on mineralised sands receive more terrestrial radiation than others, while people living or working at high altitudes receive more cosmic radiation. A lot of our natural exposure is due to radon, a gas which seeps from the earth’s crust and is present in the air we breathe.
[From the URANIUM INFORMATION CENTRE Ltd. , Melbourne, Australia]

RADATA-Interactive
A JPL/NASA WWW server providing radiation effects test data for total ionizing dose (TID) and single event effects (SEE).

Rat Haus Reality -- last modified additions/changes listing
A rapidly [as at mid-1996] growing list of references related to nuclear and other high-technology, radiation protection, hazardous waste, breast cancer and numerous other topics loosely related to "public health".

Epidemiology
[Yahoo's web page. I've been waiting since c1995 for something useful to appear here. So far (mid 1999), no luck].

Public health statements

Selected WHO press releases

Case study abstracts

Back-issues of the GEENET newsleter

Search my news archives for radiation articles
A potted glimpse query to search Aussie News articles and the news morgue for items that may be relevant to "radiation". (You might also try the potted search of my public Web pages).

Hiroshima

Chernobyl

Mururoa

Sellafield

Dounreay

Maralinga

Three Mile Island

Stuff from the US DOE

Environmental Health Perspectives Journal
The online source for Environmental Health Perspectives and other publications of the National Institute of Environmental Health Sciences, National Institutes of Health.
[See also the Search Abstracts button].

International Journal of Radiation Oncology Biology Physics (Special Issues)
Proceedings of the American Society for Therapeutic Radiology and Oncology 37th Annual Meeting; Late Effects of Normal Tissues Consensus Conference; The Faculty of Radiation Oncology of The Royal Australasian College of Radiologists; International Conference of Radiation Oncology.
[At present this seems just to be a subscription page, but we can live in hope].

Mutation research
An international journal on mutagenesis chromosome breakage and related subjects. Contents of latest edition, keyword search, etc.

Stuff from the (US) AMA
Includes online text of some past JAMA articles. Registration required to browse.

Other stuff from the US

Table of the elements, including biological significance of nuclides

Table of Nuclides

List and Glossary of medical terms (English)

Multilingual Glossary of technical and popular medical terms in nine European Languages

Random "newspaper" clippings

Radiation-Induced Cancer From Low-Dose Exposure by John W. Gofman
A review of some A-Bomb survivor research. Gofman points out potential problems in the epidemiology. He also argues that, despite public perceptions, the A-Bomb data is applicable to low-dose regimes. [See Chapter 1 for Gofman's main conclusions].

LEUKAEMIA CLUSTERS
In December 1994 the Society held a day-long symposium to consider the broad question of whether, and why, leukaemias seem to occur in clusters. Basic statistical issues were addressed, as was the aetiology and classification of, mainly human, leukaemias and lymphomas.

Ionising radiation is responsible for less than 10% of childhood leukaemias. It is generally agreed that neither waste from nuclear installations, nor the pre-conception exposure of fathers to radiation, is a likely cause of leukaemia in children. The latter theory is biologically implausible on the basis of what is known about the frequency of human gene mutations. At present, the evidence for the implication of other causes is very weak. The possibility that non-ionising radiation might be responsible is unlikely, but worthy of further exploration. There is increasing evidence that extremely low-energy electromagnetic fields can induce metabolic changes in cells, notably a change in calcium permeability across cell membranes. To suggest that this increases the risk of cancer is, as yet, without evidence, but it is possible that such electromagnetic fields may have biological effects.

THE ANNUAL REPORT OF THE RADIATION ADVISORY COMMITTEE FOR THE YEAR ENDING SEPTEMBER 1996
The Radiation Advisory Committee was established by the [Victorian] Minister for Health under the Health Act 1958 (as amended) to advise the Minister or the Chief General Manager on any matters relating to the administration of the radiation legislation referred to it by the Minister or the Chief General Manager.
[This 1996 report considers some studies relevant to power-line and EMF health effects. The overall conclusion as at this date was that effects in cell cultures have apparently been replicated, but for fields far in excess of those that should be associated with power lines or domestic appliances (including mobile phones). The report concludes there is not (yet) any good evidence for such health effects].

"Killing Our Own" by Harvey Wasserman, et al
(local HTML copy courtesy rat haus reality).

Random WWW and local resources

Incoming stuff